Anti-FBXO31 antibody
Specifications
| Product Cat#: | AB-06-1681 |
| Product type: | Primary antibody |
| Antigen: | FBXO31 |
| Immunogen: | KLH conjugated synthetic peptide derived from human FBXO31 151-250/539 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:2000) |
| Reactivity: | Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 0.01 M TBS(pH7.4) with 1% BSA; 0.03% Proclin 300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | F box only protein 31 |
| FBX14 | |
| FBX31 | |
| FBXO14 | |
| Pp2386 | |
| Putative breast cancer tumor suppressor | |
| SCF ubiquitin ligase specificity factor |
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Target information
Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in G1 arrest following DNA damage. Specifically recognizes phosphorylated cyclin-D1 (CCND1), promoting its ubiquitination and degradation by the proteasome, resulting in G1 arrest. May act as a tumor suppressor.
Provider
Erpantech Laboratory
