Anti-FBXL10 antibody
Specifications
| Product Cat#: | AB-06-1676 |
| Product type: | Primary antibody |
| Antigen: | FBXL10 |
| Immunogen: | Purified recombinant fragment of human FBXL10 expressed in E. Coli. |
| Species immunized: | Mouse |
| Isotype: | IgG2b |
| Applications: | Western Blot (1:400-1:1000); Flow Cytometry (1:100-1:200) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal, 6G-11 |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 1% BSA; 40% Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | [Histone-H3]-lysine-36 demethylase 1B antibody |
| CXXC-type zinc finger protein 2 antibody | |
| CXXC2 antibody | |
| F box and leucine rich repeat protein 10 antibody | |
| F box protein FBL10 antibody | |
| F-box and leucine-rich repeat protein 10 antibody | |
| F-box protein FBL10 antibody | |
| F-box/LRR-repeat protein 10 antibody | |
| Fbl10 antibody | |
| FBXL10 antibody | |
| JEMMA (Jumonji domain EMSY interactor methyltransferase motif) protein antibody | |
| JHDM1B antibody | |
| JmjC domain-containing histone demethylation protein 1B antibody | |
| Jumonji C domain containing histone demethylase 1B antibody | |
| Jumonji domain-containing EMSY-interactor methyltransferase motif protein antibody | |
| kdm2b antibody | |
| KDM2B_HUMAN antibody | |
| Lysine (K) specific demethylase 2B antibody | |
| Lysine-specific demethylase 2B antibody | |
| PCCX2 antibody | |
| Protein containing CXXC domain 2 antibody |
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Target information
Histone demethylase that demethylates ‘Lys-4’ and ‘Lys-36’ of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 ‘Lys-4’ and dimethylated H3 ‘Lys-36’ residue while it has weak or no activity for mono- and tri-methylated H3 ‘Lys-36’ . Preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which inhibits cell growth and proliferation . May also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex (Probable).
Provider
Erpantech Laboratory