Anti-FBP1 antibody
Specifications
| Product Cat#: | AB-06-1674 |
| Product type: | Primary antibody |
| Antigen: | FBP1 |
| Immunogen: | KLH conjugated synthetic peptide derived from human FBP1 51-150/338e |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:450-1:2000) |
| Reactivity: | Human, Mouse, Rat, Dog, Pig, Horse, Rabbit |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Preservative: 15 mM Sodium Azide, Constituents: 1% BSA; 0.01 M PBS, pH 7.4 |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | 6-bisphosphatase 1 |
| 6-bisphosphate 1-phosphohydrolase 1 | |
| D fructose 1 6 bisphosphate 1 phosphohydrolase 1 | |
| D-fructose-1 | |
| EC 3.1.3.11 | |
| F16P1_HUMAN | |
| FBP | |
| FBP1 | |
| FBPase 1 | |
| Fructose 1 6 bisphosphatase 1 | |
| Fructose bisphosphatase 1 | |
| Fructose-1 | |
| Growth inhibiting protein 17 |
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Target information
Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain.
Provider
Erpantech Laboratory
