Anti-FANCD2 antibody
Specifications
| Product Cat#: | AB-06-1663 |
| Product type: | Primary antibody |
| Antigen: | FANCD2 |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:450-1:1000); Immunohistochemistry (1:100-1:200); Immunocytochemistry (1:100-1:450); Immunoprecipitation; Immunofluorescence |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal (SN73-08) |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 1% BSA; 40% Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | DKFZp762A223 antibody |
| FA4 antibody | |
| FAD2 antibody | |
| FA4 antibody | |
| FACD2 antibody | |
| FACD2 antibody | |
| FACD antibody | |
| FACD2 antibody | |
| FACD2_HUMAN antibody | |
| FAD antibody | |
| FAD2 antibody | |
| FANCD2 antibody | |
| FANCD2 antibody | |
| FANCD antibody | |
| FANCD2 antibody | |
| Fanconi anemia complementation group D antibody | |
| Fanconi anemia complementation group D2 antibody | |
| Fanconi anemia group D2 protein antibody | |
| Fanconi pancytopenia type 4 antibody | |
| FLJ23826 antibody | |
| OTTHUMP00000158853 antibody | |
| OTTHUMP00000207925 antibody | |
| Protein FACD2 antibody | |
| Type 4 fanconi pancytopenia antibody |
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Target information
Required for maintenance of chromosomal stability. Promotes accurate and efficient pairing of homologs during meiosis. Involved in the repair of DNA double-strand breaks, both by homologous recombination and single-strand annealing. May participate in S phase and G2 phase checkpoint activation upon DNA damage. Plays a role in preventing breakage and loss of missegregating chromatin at the end of cell division, particularly after replication stress. Required for the targeting, or stabilization, of BLM to non-centromeric abnormal structures induced by replicative stress. Promotes BRCA2/FANCD1 loading onto damaged chromatin. May also be involved in B-cell immunoglobulin isotype switching.
Provider
Erpantech Laboratory
