Anti-FADD antibody
Specifications
| Product Cat#: | AB-06-1642 |
| Product type: | Primary antibody |
| Antigen: | FADD |
| Immunogen: | KLH conjugated synthetic peptide derived from human FADD 1-80/205 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2500); Immunohistochemistry-Paraffin (1:450-1:800) |
| Reactivity: | Human, Mouse, Rat, Pig |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 0.01 M TBS(pH7.4) with 1% BSA; 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | FADD protein |
| Fas-associated protein with death domain | |
| Fas associated via death domain | |
| Fas associating death domain containing protein | |
| Fas associating protein | |
| Fas associating protein with death domain | |
| FasTNFRSF6 associated via death domain | |
| GIG 3 | |
| GIG3 | |
| Growth inhibiting gene 3 protein | |
| H sapiens mRNA for mediator of receptor induced toxicity | |
| Mediator of receptor induced toxicity | |
| MGC8528 | |
| MORT1 |
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Target information
Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.
Provider
Erpantech Laboratory
