Anti-ERK1 antibody
Specifications
| Product type: | Primary antibody |
| Antigen: | ERK1 |
| Immunogen: | This antibody is produced by |
| immunizing mice with a synthetic peptide (KLHcoupled) | |
| corresponding to a region of ERK1. | |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:2000-1:10000); Immunocytochemistry (1:200-1:500) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal（7-D6-E5） |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 2mg/ml |
| Purity: | ProA affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | ERK 1 antibody |
| ERK antibody | |
| ERK-1 antibody | |
| ERK1 antibody | |
| ERT 2 antibody | |
| ERT2 antibody | |
| Extracellular Signal Regulated Kinase 1 antibody | |
| Extracellular signal related kinase 1 antibody | |
| Extracellular signal-regulated kinase 1 antibody | |
| HGNC6877 antibody | |
| HS44KDAP antibody | |
| HUMKER1A antibody | |
| Insulin Stimulated MAP2 Kinase antibody | |
| Insulin-stimulated MAP2 kinase antibody | |
| MAP kinase 1 antibody | |
| MAP kinase 3 antibody | |
| MAP Kinase antibody | |
| MAP kinase isoform p44 antibody | |
| MAPK 1 antibody | |
| MAPK 3 antibody | |
| MAPK antibody | |
| MAPK1 antibody |
Target information
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. The MAPK/ERK cascade plays also a role in initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors. About 160 substrates have already been discovered for ERKs. Many of these substrates are localized in the nucleus, and seem to participate in the regulation of transcription upon stimulation.
Provider
Erpantech Laboratory