Anti-ERCC5 antibody
Specifications
| Product Cat#: | AB-07-0487 |
| Product type: | Primary antibody |
| Antigen: | ERCC5 |
| Immunogen: | A synthetic peptide derived from human ERCC5 . The exact amino-acid sequence is proprietary. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot: 1:500~1:3000 Immunofluorescence: 1:100~1:500 ELISA: 1:20000 |
| Reactivity: | Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Antigen affinity chromatography |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Alternative names: | ERCC5 /GTPase ERas [Precursor]; E-Ras; Embryonic stem cell-expressed Ras; ERAS; HRAS2, HRASP |
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Target information
Single-stranded structure-specific DNA endonuclease involved in DNA excision repair. Makes the 3’incision in DNA nucleotide excision repair (NER). Acts as a cofactor for a DNA glycosylase that removes oxidized pyrimidines from DNA. May also be involved in transcription-coupled repair of this kind of damage, in transcription by RNA polymerase II, and perhaps in other processes too (By similarity).
Provider
Erpantech Laboratory
