Anti-Ephrin B2 antibody
Specifications
| Product type: | Primary antibody |
| Antigen: | Ephrin B2 |
| Immunogen: | recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:200-1:1500); Immunofluorescence(1:50-1:200); ICC Immunocytochemistry (1:50-1:200) |
| Reactivity: | Human kidney, mouse lung, rat brain, Hela, 293T. |
| Clonality (clone number): | Monoclonal(JM53-21) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1mg/ml |
| Purity: | Protein A purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | EFN B2 antibody |
| EFNB 2 antibody | |
| Efnb2 antibody | |
| EFNB2_HUMAN antibody | |
| Eph related receptor tyrosine kinase ligand 5 antibody | |
| EPH-related receptor tyrosine kinase ligand 5 antibody | |
| ephrin B2 antibody | |
| Ephrin-B2 antibody | |
| EphrinB2 antibody | |
| EPLG 5 antibody | |
| HTK ligand antibody | |
| HTK-L antibody | |
| HTKL antibody | |
| LERK 5 antibody | |
| Ligand of eph related kinase 5 antibody | |
| OTTMUSP00000024973 antibody |
Target information
Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. May play a role in constraining the orientation of longitudinally projecting axons.
Provider
Erpantech Laboratory