Anti-EMD antibody
Specifications
| Product Cat#: | AB-06-1538 |
| Product type: | Primary antibody |
| Antigen: | EMD |
| Immunogen: | Recombinant protein |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot ( 1:800-1:2000 ); Immunohistochemistry ( 1:80-1:200 ); Immunocytochemistry ( 1:80-1:200 ); Flow Cytometry ( 1:40-1:100 ) |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Monoclonal ( A8-F5 ) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer ( pH7.4 ), 1 % BSA, 40 % glycerol, 0.05 % NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | EDMD Antibody |
| Emd Antibody | |
| EMD_HUMAN Antibody | |
| Emerin Antibody | |
| Emery Dreifuss Muscular Dystrophy Antibody | |
| STA antibody |
Show More
Target information
Stabilizes and promotes the formation of a nuclear actin cortical network. Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments. Inhibits beta-catenin activity by preventing its accumulation in the nucleus. Acts by influencing the nuclear accumulation of beta-catenin through a CRM1-dependent export pathway. Links centrosomes to the nuclear envelope via a microtubule association. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with the viral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires the presence of BAF and EMD. Required for proper localization of non-farnesylated prelamin-A/C.
Provider
Erpantech Laboratory
