Anti-E-cadherin antibody
Specifications
| Product Cat#: | AB-06-1489 |
| Product type: | Primary antibody |
| Antigen: | E-cadherin |
| Immunogen: | Recombinant protein |
| Species immunized: | Mouse |
| Isotype: | IgG2b |
| Applications: | Western Blot ( 1:800-1:2000 ); Immunohistochemistry ( 1:80-1:200 ); Immunocytochemistry ( 1:80-1:200 ); Flow Cytometry ( 1:80-1:200 ) |
| Reactivity: | Mouse and Human |
| Clonality (clone number): | Monoclonal ( 3-F9 ) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer ( pH7.4 ), 1 % BSA, 40 % glycerol, 0.05 % NaN3. |
| Concentration: | 2 mg/ml |
| Purity: | Protein G affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Arc 1 Antibody |
| CADH1_HUMAN Antibody | |
| Cadherin 1 Antibody | |
| cadherin 1 type 1 E-cadherin Antibody | |
| Cadherin1 Antibody | |
| CAM 120/80 Antibody | |
| CD 324 Antibody | |
| CD324 Antibody | |
| CD324 Antigen Antibody | |
| cdh1 Antibody | |
| CDHE Antibody | |
| E-Cad/CTF3 Antibody | |
| E-cadherin Antibody | |
| ECAD Antibody | |
| Epithelial Cadherin Antibody | |
| epithelial Calcium Dependant Adhesion Protein Antibody | |
| LCAM Antibody | |
| Liver Cell aAdhesion Molecule Antibody | |
| UVO Antibody | |
| Uvomorulin Antibody |
Target information
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7 (By similarity).E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production (By similarity).(Microbial infection) Does not function as a receptor for L.monocytogenes internalin A (InlA); mutating a single surface-exposed residue confers receptor activity to this protein and promotes uptake of the bacteria.
Provider
Erpantech Laboratory