Anti-DYNLL1 antibody
Specifications
| Product Cat#: | AB-06-1471 |
| Product type: | Primary antibody |
| Antigen: | DYNLL1 |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:800-1:2000); Immunohistochemistry (1:100-1:200); Immunocytochemistry (1:100-1:200); Immunofluorescence; Immunoprecipitation |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal (SD08-04) |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | 8 kDa dynein light chain antibody |
| 8kDLC antibody | |
| Cytoplasmic dynein light polypeptide antibody | |
| DLC1 antibody | |
| DLC8 antibody | |
| DNCL1 antibody | |
| DNCLC1 antibody | |
| DYL1_HUMAN antibody | |
| Dynein , cytoplasmic, light chain 1 antibody | |
| Dynein light chain 1 cytoplasmic antibody | |
| Dynein light chain 1, cytoplasmic antibody | |
| Dynein light chain LC8 type 1 antibody | |
| Dynein light chain LC8-type 1 antibody | |
| Dynein, cytoplasmic, light polypeptide 1 antibody | |
| Dynein, light chain, LC8-type 1 antibody | |
| DYNLL1 antibody | |
| HDLC1 antibody | |
| LC8 antibody | |
| LC8a antibody | |
| MGC126137 antibody | |
| MGC126138 antibody | |
| MGC72986 antibody | |
| PIN antibody | |
| Protein inhibitor of neuronal nitric oxide synthase antibody | |
| Protein inhibitor of neuronal NOS antibody |
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Target information
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.
Binds and inhibits the catalytic activity of neuronal nitric oxide synthase.
Promotes transactivation functions of ESR1 and plays a role in the nuclear localization of ESR1.
Regulates apoptotic activities of BCL2L11 by sequestering it to microtubules. Upon apoptotic stimuli the BCL2L11-DYNLL1 complex dissociates from cytoplasmic dynein and translocates to mitochondria and sequesters BCL2 thus neutralizing its antiapoptotic activity.
Provider
Erpantech Laboratory
