Anti-DR5 antibody
Specifications
| Product Cat#: | AB-06-1450 |
| Product type: | Primary antibody |
| Antigen: | DR5 |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:1000); Immunohistochemistry (1:100-1:200); Flow Cytometry (1:50-1:200); Immunoprecipitation |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (JA03-38) |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Fas like protein antibody |
| Apoptosis inducing protein TRICK2A/2B antibody | |
| Apoptosis inducing receptor TRAIL R2 antibody | |
| CD262 antibody | |
| CD262 antigen antibody | |
| Cytotoxic TRAIL receptor 2 antibody | |
| Death domain containing receptor for TRAIL/Apo 2L antibody | |
| Death receptor 5 antibody | |
| DR5 antibody | |
| KILLER antibody | |
| KILLER/DR5 antibody | |
| OTTHUMP00000123492 antibody | |
| OTTHUMP00000123493 antibody | |
| P53 regulated DNA damage inducible cell death receptor(killer) antibody | |
| TNF related apoptosis inducing ligand receptor 2 antibody | |
| TNF-related apoptosis-inducing ligand receptor 2 antibody | |
| TNFRSF10B antibody | |
| TR10B_HUMAN antibody | |
| TRAIL R2 antibody | |
| TRAIL receptor 2 antibody | |
| TRAIL-R2 antibody | |
| TRAILR2 antibody | |
| TRICK2 antibody | |
| TRICK2A antibody | |
| TRICK2B antibody | |
| TRICKB antibody | |
| Tumor necrosis factor receptor like protein ZTNFR9 antibody | |
| Tumor necrosis factor receptor superfamily member 10B antibody | |
| Tumor necrosis factor receptor superfamily, member 10b antibody | |
| ZTNFR9 antibody |
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Target information
Receptor for the cytotoxic ligand TNFSF10/TRAIL (PubMed:10549288). The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis.
Provider
Erpantech Laboratory