Anti-DR4 antibody
Specifications
| Product Cat#: | AB-06-1449 |
| Product type: | Primary antibody |
| Antigen: | DR4 |
| Immunogen: | KLH conjugated synthetic peptide derived from human DR4 401-468/468 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:2000); Immunohistochemistry-Paraffin (1:500-1:800) |
| Reactivity: | Human, Rat |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 10 mM TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Apo 2 |
| Apo2 | |
| CD 261 | |
| CD261 | |
| CD261 antigen | |
| Cytotoxic ligand TRAIL receptor | |
| Cytotoxic TRAIL receptor | |
| Death receptor 4 | |
| DR 4 | |
| DR4 | |
| MGC9365 | |
| NF related apoptosis-inducing ligand receptor 1 | |
| T10A | |
| TNF related apoptosis inducing ligand receptor 1 | |
| TNFRSF10A | |
| TRAIL R1 | |
| TRAIL receptor 1 | |
| TRAILR 1 | |
| TRAILR1 | |
| Tumor necrosis factor receptor superfamily member 10a | |
| Tumor necrosis factor receptor superfamily member 10A precursor |
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Target information
Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B.
Provider
Erpantech Laboratory
