Anti-Dnmt3a antibody
Specifications
| Product Cat#: | AB-06-1422 |
| Product type: | Primary antibody |
| Antigen: | Dnmt3a |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:800-1:2000); Immunocytochemistry (1:100-1:200); Immunofluorescence |
| Reactivity: | Human, Rat |
| Clonality (clone number): | Monoclonal (ST04-78) |
| Form: | Liquid |
| Buffer: | 1*TBS (pH 7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | DNA (cytosine 5) methyltransferase 3 alpha antibody |
| DNA (cytosine 5) methyltransferase 3A antibody | |
| DNA (cytosine-5)-methyltransferase 3A antibody | |
| DNA cytosine methyltransferase 3A2 antibody | |
| DNA methyltransferase 3 alpha antibody | |
| DNA methyltransferase 3a antibody | |
| DNA methyltransferase HsaIIIA antibody | |
| DNA MTase HsaIIIA antibody | |
| DNM3A_HUMAN antibody | |
| DNMT 3a antibody | |
| DNMT antibody | |
| Dnmt3a antibody | |
| DNMT3A2 antibody | |
| M.HsaIIIA antibody | |
| MCMT antibody | |
| OTTHUMP00000201149 antibody | |
| TBRS antibody |
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Target information
Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. Plays a role in paternal and maternal imprinting. Required for methylation of most imprinted loci in germ cells. Acts as a transcriptional corepressor for ZBTB18. Recruited to trimethylated ‘Lys-36’ of histone H3 (H3K36me3) sites. Can actively repress transcription through the recruitment of HDAC activity.
Provider
Erpantech Laboratory