Anti-DLK1 antibody
Specifications
| Product Cat#: | AB-06-1394 |
| Product type: | Primary antibody |
| Antigen: | DLK1 |
| Immunogen: | Purified recombinant fragment of human DLK1 expressed in E. Coli. |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:400-1:1000); Flow Cytometry (1:50-1:200); Immunocytochemistry (1:100-1:200) |
| Reactivity: | Human, Mouse |
| Clonality (clone number): | Monoclonal (D2-A3) |
| Form: | Liquid |
| Buffer: | 1*TBS (pH 7.4), 1% BSA, Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Adipocyte differentiation inhibitor protein antibody |
| Brevideltin antibody | |
| Delta like 1 homolog antibody | |
| Delta like homolog antibody | |
| Delta like protein antibody | |
| Delta1 antibody | |
| DLK 1 antibody | |
| DLK antibody | |
| DLK-1 antibody | |
| DLK1 antibody | |
| DLK1_HUMAN antibody | |
| FA 1 antibody | |
| FA1 antibody | |
| Fetal antigen 1 antibody | |
| PG2 antibody | |
| Preadipocyte factor 1 antibody | |
| Pref 1 antibody | |
| Pref antibody | |
| Pref1 antibody | |
| Protein delta homolog 1 antibody | |
| Secredeltin antibody | |
| ZOG antibody |
Target information
The DLK1 protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This proteins’ gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass.
Provider
Erpantech Laboratory
