Anti-DIS3L2 antibody
Specifications
| Product Cat#: | AB-06-1386 |
| Product type: | Primary antibody |
| Antigen: | DIS3L2 |
| Immunogen: | Purified recombinant fragment of human DIS3L2 expressed in E. Coli. |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:400-1:1000); Immunohistochemistry (1:100-1:200); Flow Cytometry (1:50-1:200) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (B2-C7) |
| Form: | Liquid |
| Buffer: | 1*TBS (pH 7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | DI3L2_HUMAN antibody |
| DIS3 L2 antibody | |
| DIS3 mitotic control homolog (S. cerevisiae) like 2 antibody | |
| DIS3 mitotic control homolog like 2 antibody | |
| DIS3-like exonuclease 2 antibody | |
| Dis3l2 antibody | |
| FLJ36974 antibody | |
| MGC42174 antibody |
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Target information
3′-5′-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3′ end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3′. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mitosis, and negatively regulates cell proliferation.
Provider
Erpantech Laboratory
