Anti-Dio3 antibody
Specifications
| Product Cat#: | AB-06-1385 |
| Product type: | Primary antibody |
| Antigen: | Dio3 |
| Immunogen: | KLH conjugated synthetic peptide derived from human Dio3 51-150/278 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:2000) |
| Reactivity: | Human, Mouse, Rat, Dog, Pig, Cow, Sheep |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 0.01 M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Type 3 DI |
| D3 | |
| 5DIII | |
| Deiodinase iodothyronine type 3 | |
| Deiodinase iodothyronine type III | |
| Dio 3 | |
| DIOIII | |
| MGC124117 | |
| MGC124118 | |
| TXDI3 | |
| Type III 5' deiodinase |
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Target information
Responsible for the deiodination of T4 (3,5,3′,5′-tetraiodothyronine) into RT3 (3,3′,5′-triiodothyronine) and of T3 (3,5,3′-triiodothyronine) into T2 (3,3′-diiodothyronine). RT3 and T2 are inactive metabolites. May play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones. Can regulate circulating fetal thyroid hormone concentrations throughout gestation. Essential role for regulation of thyroid hormone inactivation during embryological development.
Provider
Erpantech Laboratory
