Anti-DIAPH3 antibody
Specifications
| Product Cat#: | AB-06-1382 |
| Product type: | Primary antibody |
| Antigen: | DIAPH3 |
| Immunogen: | Synthetic peptide within human DIAPH3 aa 1-50. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400); Immunohistochemistry (1:100-1:200); Flow Cytometry (1:50-1:200); Immunocytochemistry (1:100-1:200) |
| Reactivity: | Human, Mouse |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1mg/ml |
| Purity: | Peptide affinity purified. |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | AN antibody |
| AUNA1 antibody | |
| Dia2 antibody | |
| Diap3 antibody | |
| DIAP3_HUMAN antibody | |
| DIAPH3 antibody | |
| Diaphanous homolog 3 (Drosophila) antibody | |
| Diaphanous homolog 3 antibody | |
| Diaphanous related formin 3 antibody | |
| Drosophila, homolog of, 3 antibody | |
| Diaphanous-related formin-3 antibody | |
| DKFZp434C0931 antibody | |
| DKFZp686A13178 antibody | |
| DRF3 antibody | |
| FLJ34705 antibody | |
| MDia2 antibody | |
| NSDAN antibody | |
| OTTHUMP00000018480 antibody | |
| Protein diaphanous homolog 3 antibody | |
| RP11-26P21.1 antibody |
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Target information
Actin nucleation and elongation factor required for the assembly of F-actin structures, such as actin cables and stress fibers. Required for cytokinesis, stress fiber formation and transcriptional activation of the serum response factor. Binds to GTP-bound form of Rho and to profilin: acts in a Rho-dependent manner to recruit profilin to the membrane, where it promotes actin polymerization. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics. Also acts as an actin nucleation and elongation factor in the nucleus by promoting nuclear actin polymerization inside the nucleus to drive serum-dependent SRF-MRTFA activity.
Provider
Erpantech Laboratory
