Anti-DHX36 antibody
Specifications
| Product Cat#: | AB-06-1378 |
| Product type: | Primary antibody |
| Antigen: | DHX36 |
| Immunogen: | KLH conjugated synthetic peptide derived from human DHX36 151-250/1008 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:2000); Immunohistochemistry-Paraffin (1:500-1:800) |
| Reactivity: | Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 0.01 M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | DDX36 |
| DEAH box protein 36 | |
| Dhx36 | |
| DHX36_HUMAN | |
| EC 3.6.1.- | |
| KIAA1488 | |
| MLE like protein 1 | |
| MLE-like protein 1 | |
| MLEL1 | |
| Probable ATP dependent RNA helicase DHX36 | |
| Probable ATP-dependent RNA helicase DHX36 | |
| RHAU | |
| RNA helicase associated with AU rich element ARE |
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Target information
Multifunctional ATP-dependent helicase that unwinds G-quadruplex (G4) structures. Plays a role in many biological processes such as genomic integrity, gene expression regulations and as a sensor to initiate antiviral responses. G4 structures correspond to helical structures containing guanine tetrads (By similarity). Binds with high affinity to and unwinds G4 structures that are formed in nucleic acids. Plays a role in genomic integrity . Converts the G4-RNA structure present in telomerase RNA template component (TREC) into a double-stranded RNA to promote P1 helix formation that acts as a template boundary ensuring accurate reverse transcription. Plays a role in transcriptional regulation.
Provider
Erpantech Laboratory