Anti-DHRS2 antibody
Specifications
| Product Cat#: | AB-06-1376 |
| Product type: | Primary antibody |
| Antigen: | DHRS2 |
| Immunogen: | KLH conjugated synthetic peptide derived from human DHRS2 61-160/258 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:2000) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 0.01 M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Dehydrogenase/reductase (SDR family) member 2 |
| Dehydrogenase/reductase member 2 | |
| Dehydrogenase/reductase SDR family member 2 | |
| Dicarbonyl reductase HEP27 | |
| DHRSⅡ | |
| Hep27 | |
| HEP27 protein | |
| Protein D | |
| SDR family member | |
| SDR25C1 | |
| Short chain alcohol dehydrogenase family member | |
| Short chain dehydrogenase/reductase family 25C member 1 |
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Target information
Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2-propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. Attenuates MDM2-mediated p53/TP53 degradation, leading to p53/TP53 stabilization and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21.
Provider
Erpantech Laboratory
