Anti-Deformed Epidermal Autoregulatory Factor 1 antibody
Specifications
| Product Cat#: | AB-06-1349 |
| Product type: | Primary antibody |
| Antigen: | Deformed Epidermal Autoregulatory Factor 1 |
| Immunogen: | KLH conjugated synthetic peptide derived from human Deformed Epidermal Autoregulatory Factor 1 211-310/565 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:2000) |
| Reactivity: | Mouse, Rat, Chicken, Dog, Cow, Horse |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 0.01 M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | DEAF1 |
| Deformed epidermal autoregulatory factor 1 homolog | |
| Nuclear DEA1 related transcriptional regulator | |
| NUDR | |
| SPN | |
| Suppressin | |
| Zinc finger MYND domain containing protein 5 | |
| ZMYND5 |
Target information
Transcription factor that binds to sequence with multiple copies of 5′-TTC[CG]G-3′ present in its own promoter and that of the HNRPA2B1 gene. Down-regulates transcription of these genes. Binds to the retinoic acid response element (RARE) 5′-AGGGTTCACCGAAAGTTCA-3′. Activates the proenkephalin gene independently of promoter binding, probably through protein-protein interaction. When secreted, behaves as an inhibitor of cell proliferation, by arresting cells in the G0 or G1 phase. Required for neural tube closure and skeletal patterning. Regulates epithelial cell proliferation and side-branching in the mammary gland. Controls the expression of peripheral tissue antigens in pancreatic lymph nodes. Isoform 1 displays greater transcriptional activity than isoform 4. Isoform 4 may inhibit transcriptional activity of isoform 1 by interacting with isoform 1 and retaining it in the cytoplasm. Transcriptional activator of EIF4G3.
Provider
Erpantech Laboratory
