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Anti-DDX6 antibody

SKU Product Brand Unit Availability Price Quantity  
AB-06-1348
Anti-DDX6 antibody
Erpan Tech In stock

Specifications        

Product Cat#: AB-06-1348
Product type: Primary antibody
Antigen: DDX6
Immunogen: Recombinant protein
Species immunized: Rabbit
Isotype: IgG
Applications: Western Blot (1:400-1:1000); Immunohistochemistry (1:50-1:200)
Reactivity: Human, Mouse, Rat
Clonality (clone number): Monoclonal (JB41-32)
Form: Liquid
Buffer: 1*TBS (pH 7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration: 1 mg/ml
Purity: Protein A affinity purified
Storage: Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles.
Alternative names: ATP dependent RNA helicase DDX6 antibody
ATP dependent RNA helicase p54 antibody
DDX6 antibody
DEAD (Asp Glu Ala Asp) box polypeptide 6 antibody
DEAD box 6 antibody
DEAD box protein 6 antibody
DEAD/H (Asp Glu Ala Asp/His) box polypeptide 6 (RNA helicase 54kD) antibody
FLJ36338 antibody
HLR2 antibody
Oncogene RCK antibody
P54 antibody
Probable ATP-dependent RNA helicase DDX6 antibody
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Target information

RCK, also known as DDX6 and P54, is a member of the DEAD-box RNA helicase family of proteins, all of which share common protein motifs. Found in most tissues, RCK is an unwindase that exhibits ATP-dependent RNA un-winding activity, as well as the ability to decay RNA in the 5′-3′ direction. In non-malignant cells, RCK is associated with all processes of normal RNA metabolism including splicing, export and translation initiation. Mutations in the gene encoding RCK can cause the protein to be overexpressed, changing its function to that of an oncogene that positively regulates the expression of genes involved in cell growth and proliferation. It is believed that, through its unwindase activity, the main function of RCK is to downregulate mRNA expression and maintain normal transcriptional levels within the cell.

Provider

Erpantech Laboratory

Download

MSDS-AB-06-1348.pdf (181 downloads )