Anti-DAP12 antibody
Specifications
| Product Cat#: | AB-06-1315 |
| Product type: | Primary antibody |
| Antigen: | DAP12 |
| Immunogen: | Synthetic peptide within human DAP12 aa 60-100. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:1500); Immunohistochemistry (1:100-1:200); Flow Cytometry (1:50-1:150) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (JG38-70) |
| Form: | Liquid |
| Buffer: | 1*TBS (pH 7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | DAP 12 antibody |
| DAP12 antibody | |
| DNAX activation protein 12 antibody | |
| DNAX-activation protein 12 antibody | |
| KAR-associated protein antibody | |
| KARAP antibody | |
| Killer activating receptor associated protein antibody | |
| Killer-activating receptor-associated protein antibody | |
| PLOSL antibody | |
| TYOBP_HUMAN antibody | |
| TYRO protein tyrosine kinase binding protein antibody | |
| TYRO protein tyrosine kinase-binding protein antibody | |
| TYROBP antibody |
Target information
Adapter protein which non-covalently associates with activating receptors found on the surface of a variety of immune cells to mediate signaling and cell activation following ligand binding by the receptors. TYROBP is tyrosine-phosphorylated in the ITAM domain following ligand binding by the associated receptors which leads to activation of additional tyrosine kinases and subsequent cell activation . Also has an inhibitory role in some cells . Non-covalently associates with activating receptors of the CD300 family to mediate cell activation . Also mediates cell activation through association with activating receptors of the CD200R family (By similarity). Required for neutrophil activation mediated by integrin (By similarity). Required for the activation of myeloid cells mediated by the CLEC5A/MDL1 receptor .
Provider
Erpantech Laboratory