Anti-Cyclin H antibody
Specifications
| Product Cat#: | AB-06-1237 |
| Product type: | Primary antibody |
| Antigen: | Cyclin H |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:1000-1:5000); Immunohistochemistry (1:50-1:200); Immunocytochemistry (1:100-1:500); Flow Cytometry (1:50-1:100); Immunofluorescence |
| Reactivity: | Human, Mouse |
| Clonality (clone number): | Monoclonal (SN20-48) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | 6330408H09Rik antibody |
| AI661354 antibody | |
| AV102684 antibody | |
| AW538719 antibody | |
| CAK antibody | |
| CAK complex subunit antibody | |
| ccnh antibody | |
| CCNH_HUMAN antibody | |
| CDK activating kinase antibody | |
| CDK activating kinase complex subunit antibody | |
| Cyclin dependent kinase activating kinase antibody | |
| cyclin dependent kinase activating kinase complex subunit antibody | |
| Cyclin H antibody | |
| Cyclin-H antibody | |
| CyclinH antibody | |
| MO15 associated protein antibody | |
| MO15-associated protein antibody | |
| p34 antibody | |
| p36 antibody | |
| p37 antibody |
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Target information
Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.
Provider
Erpantech Laboratory