Anti-CXCR4 antibody
Specifications
| Product Cat#: | AB-06-1211 |
| Product type: | Primary antibody |
| Antigen: | CXCR4 |
| Immunogen: | Peptide |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:1000); Flow Cytometry (1:50-1:100); Immunohistochemistry (1:50-1:200); Immunocytochemistry (1:500-1:2000) |
| Reactivity: | Human, Rat |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 0.5% BSA, 50% glycerol, 0.05% NaN3. |
| Concentration: | 1mg/ml |
| Purity: | Peptide affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | C-X-C chemokine receptor type 4 antibody |
| CD184 antibody | |
| CD184 antigen antibody | |
| Chemokine (C X C motif) receptor 4 antibody | |
| Chemokine CXC Motif Receptor 4 antibody | |
| CXC-R4 antibody | |
| CXCR-4 antibody | |
| CXCR4 antibody | |
| CXCR4_HUMAN antibody | |
| D2S201E antibody | |
| FB22 antibody | |
| Fusin antibody | |
| HM89 antibody | |
| HSY3RR antibody | |
| LAP 3 antibody | |
| LAP3 antibody | |
| LCR1 antibody | |
| LESTR antibody | |
| Leukocyte derived seven transmembrane domain receptor antibody | |
| Leukocyte-derived seven transmembrane domain receptor antibody | |
| Lipopolysaccharide associated protein 3 antibody | |
| Neuropeptide Y receptor Y3 antibody | |
| NPY3R antibody | |
| NPYR antibody | |
| NPYRL antibody | |
| NPYY3 antibody | |
| NPYY3R antibody | |
| Probable G protein coupled receptor lcr1 homolog antibody | |
| SDF 1 receptor antibody | |
| SDF-1 receptor antibody | |
| SEVEN-TRANSMEMBRANE-SEGMENT RECEPTOR antibody | |
| Stromal cell derived factor 1 receptor antibody | |
| Stromal cell-derived factor 1 receptor antibody | |
| WHIM antibody | |
| WHIMS antibody |
Target information
Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation (PubMed:10452968, PubMed:28978524, PubMed:18799424, PubMed:24912431). Involved in the AKT signaling cascade (PubMed:24912431). Plays a role in regulation of cell migration, e.g. during wound healing (PubMed:28978524). Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels (PubMed:20228059). Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes (PubMed:11276205). Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival (By similarity).
Provider
Erpantech Laboratory