Anti-COX2 antibody
Specifications
| Product type: | Primary antibody |
| Antigen: | COX2 |
| Immunogen: | Synthetic peptide corresponding to C-terminal of Human COX1/Cyclooxygenase 1 |
| Species immunized: | Mouse |
| Isotype: | IgG |
| Applications: | Western Blot (1:100-1:1000); Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 ml of cell lysate) ); ELISA (1:30-1:3000); Immunohistochemistry (1:50-1:500 ); Immunofluorescence (1:50-1:500) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1mg/ml |
| Purity: | Immunogen affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | COX 2 antibody |
| COX-2 antibody | |
| COX2 antibody | |
| Cyclooxygenase 2 antibody | |
| Cyclooxygenase 2b antibody | |
| Cyclooxygenase antibody | |
| Cyclooxygenase-2 antibody | |
| Cyclooxygenase2 antibody | |
| EC 1.14.99.1 antibody | |
| fj02a10 antibody | |
| Glucocorticoid-regulated inflammatory cyclooxygenase antibody | |
| Glucocorticoid-regulated inflammatory Prostaglandin G/H synthase antibody | |
| GRIPGHS antibody | |
| hCox 2 antibody | |
| Macrophage activation-associated marker protein P71/73 antibody | |
| OTTHUMP00000033524 antibody | |
| PES-2 antibody | |
| PGG/HS antibody | |
| PGH synthase 2 antibody | |
| PGH2_HUMAN antibody | |
| PGHS 2 antibody | |
| PGHS-2 antibody | |
| PGHS2 antibody | |
| PHS 2 antibody | |
| PHS II antibody | |
| PHS2 antibody | |
| Prostaglandin endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) antibody | |
| Prostaglandin endoperoxide synthase 2 antibody | |
| Prostaglandin G/H synthase 2 antibody | |
| Prostaglandin G/H synthase 2 precursor antibody | |
| Prostaglandin G/H synthase and cyclooxygenase antibody | |
| Prostaglandin G/H synthase antibody | |
| Prostaglandin H2 synthase 2 antibody | |
| prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) antibody | |
| Prostaglandin-endoperoxide synthase 2 antibody | |
| PTGS2 antibody | |
| ptgs2a antibody | |
| TIS10 antibody | |
| TIS10 protein antibody |
Target information
Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis (PubMed:26859324, PubMed:27226593). Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis. During neuroinflammation, plays a role in neuronal secretion of specialized preresolving mediators (SPMs), especially 15-R-lipoxin A4, that regulates phagocytic microglia (By similarity).
Provider
Erpantech Laboratory
