Anti-Cox1 antibody
Specifications
| Product Cat#: | AB-07-0359 |
| Product type: | Primary antibody |
| Antigen: | Cox1 |
| Immunogen: | A synthetic peptide derived from human Cox1. The exact amino-acid sequence is proprietary. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:200-1:2500); Immunohistochemistry (1:50-1:100); ELISA (1:40000) |
| Reactivity: | Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | PBS (without Mg2+ and Ca2+ ), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Antigen affinity chromatography |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Alternative names: | COX3; PCOX1; CYCLOOXYGENASE 1; PARTIAL COX1 PROTEINS; PGHS1 CYCLOOXYGENASE 3; PROSTAGLANDIN G/H SYNTHASE 1; Prostaglandin-endoperoxide synthase 1 |
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Target information
Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Involved in the constitutive production of prostanoids in particular in the stomach and platelets. In gastric epithelial cells, it is a key step in the generation of prostaglandins, such as prostaglandin E2 (PGE2), which plays an important role in cytoprotection. In platelets, it is involved in the generation of thromboxane A2 (TXA2), which promotes platelet activation and aggregation, vasoconstriction and proliferation of vascular smooth muscle cells.
Provider
Erpantech Laboratory
