Anti-CHD1 antibody
Specifications
| Product type: | Primary antibody |
| Antigen: | CHD1 |
| Immunogen: | Recombinant protein |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:900); Immunohistochemistry (1:90) |
| Reactivity: | Human, Mouse |
| Clonality (clone number): | Monoclonal (2-2) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 2mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | ATP dependent helicase CHD 1 antibody |
| ATP-dependent helicase CHD1 antibody | |
| CHD 1 antibody | |
| CHD-1 antibody | |
| Chd1 antibody | |
| CHD1_HUMAN antibody | |
| Chromodomain helicase DNA binding protein 1 antibody | |
| Chromodomain-helicase-DNA-binding protein 1 antibody | |
| DKFZp686E2337 antibody | |
| OTTHUMP00000222625 antibody |
Target information
ATP-dependent chromatin-remodeling factor which functions as substrate recognition component of the transcription regulatory histone acetylation (HAT) complex SAGA. Regulates polymerase II transcription. Also required for efficient transcription by RNA polymerase I, and more specifically the polymerase I transcription termination step. Regulates negatively DNA replication. Not only involved in transcription-related chromatin-remodeling, but also required to maintain a specific chromatin configuration across the genome. Is also associated with histone deacetylase (HDAC) activity (By similarity). Required for the bridging of SNF2, the FACT complex, the PAF complex as well as the U2 snRNP complex to H3K4me3. Functions to modulate the efficiency of pre-mRNA splicing in part through physical bridging of spliceosomal components to H3K4me3. Required for maintaining open chromatin and pluripotency in embryonic stem cells (By similarity).
Provider
Erpantech Laboratory
