Anti-CENPC antibody
Specifications
| Product Cat#: | AB-06-1027 |
| Product type: | Primary antibody |
| Antigen: | CENPC |
| Immunogen: | Recombinant protein within human CENPC aa 400-600. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:2000); Immunohistochemistry (1:40-1:200); Flow Cytometry (1:40-1:200); Immunocytochemistry (1:40-1:200); Immunoprecipitation (1:20-1:50); Immunofluorescence |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (JG36-15) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% Glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | CENP-C 1 antibody |
| CENP-C antibody | |
| CENPC_HUMAN antibody | |
| CENPC1 antibody | |
| Centromere autoantigen C antibody | |
| Centromere autoantigen C1 antibody | |
| Centromere protein C 1 antibody | |
| Centromere protein C antibody | |
| Hcp-4 antibody | |
| ICEN7 antibody | |
| Interphase centromere complex protein 7 antibody | |
| MIF2 antibody |
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Target information
Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPC recruits DNA methylation and DNMT3B to both centromeric and pericentromeric satellite repeats and regulates the histone code in these regions.
Provider
Erpantech Laboratory