Anti-CDK2 antibody
Specifications
| Product Cat#: | AB-06-1000 |
| Product type: | Primary antibody |
| Antigen: | CDK2 |
| Immunogen: | Peptide |
| Species immunized: | Mouse |
| Isotype: | IgG2b |
| Applications: | Western Blot (1:1800); Immunocytochemistry (1:450); Immunohistochemistry; Flow Cytometry |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal (10-D7) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% Glycerol, 0.05% NaN3. |
| Concentration: | 2 mg/ml |
| Purity: | Protein G affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Cdc2 related protein kinase antibody |
| Cdc2-related protein kinase antibody | |
| CDC28 antibody | |
| CDC2A antibody | |
| Cdk 2 antibody | |
| CDK1 antibody | |
| CDK2 antibody | |
| CDK2_HUMAN antibody | |
| CDKN2 antibody | |
| Cell devision kinase 2 antibody | |
| Cell division protein kinase 2 antibody | |
| Cyclin dependent kinase 2 antibody | |
| Cyclin dependent kinase 2-alpha antibody | |
| Cyclin-dependent kinase 2 antibody | |
| kinase Cdc2 antibody | |
| MPF antibody | |
| P33 protein kinase antibody | |
| P33(CDK2) antibody |
Target information
Serine/threonine-protein kinase involved in the control of the cell cycle; essential for meiosis, but dispensable for mitosis. Phosphorylates CTNNB1, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2. Triggers duplication of centrosomes and DNA. Acts at the G1-S transition to promote the E2F transcriptional program and the initiation of DNA synthesis, and modulates G2 progression; controls the timing of entry into mitosis/meiosis by controlling the subsequent activation of cyclin B/CDK1 by phosphorylation, and coordinates the activation of cyclin B/CDK1 at the centrosome and in the nucleus. Crucial role in orchestrating a fine balance between cellular proliferation, cell death, and DNA repair in human embryonic stem cells (hESCs).
Provider
Erpantech Laboratory