Anti-CD71 antibody
Specifications
| Product Cat#: | AB-06-0951 |
| Product type: | Primary antibody |
| Antigen: | CD71 |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Immunohistochemistry ( 1:50-1:200 ); Immunocytochemistry/Immunofluorescence ( 1:50-1:200 ); Flow Cytometry ( 1:50-1:100 ) |
| Reactivity: | Mouse and Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer ( pH7.4 ), 1 % BSA, 40 % glycerol, 0.05 % NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | CD 71 Antibody |
| CD71 Antibody | |
| CD71 Antigen Antibody | |
| IMD46 Antibody | |
| OTTHUMP00000208523 Antibody | |
| OTTHUMP00000208524 Antibody | |
| OTTHUMP00000208525 Antibody | |
| p90 Antibody | |
| sTfR Antibody | |
| T9 Antibody | |
| TFR 1 Antibody | |
| TfR Antibody | |
| TfR1 Antibody | |
| TFR1_HUMAN Antibody | |
| TFRC Antibody | |
| Transferrin Receptor (p90 CD71) Antibody | |
| Transferrin Receptor Protein 1, Serum Form Antibody | |
| Trfr Antibody |
Target information
Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site. Positively regulates T and B cell proliferation through iron uptake.(Microbial infection) Acts as a receptor for new-world arenaviruses: Guanarito, Junin and Machupo virus.
Provider
Erpantech Laboratory
