Anti-CD6 antibody
Specifications
| Product Cat#: | AB-06-0940 |
| Product type: | Primary antibody |
| Antigen: | CD6 |
| Immunogen: | Recombinant protein |
| Species immunized: | Mouse |
| Isotype: | IgG2b |
| Applications: | Western Blot (1:700-1:2100); Immunohistochemistry (1:70-1:210); Immunocytochemistry (1:80-1:240); Flow Cytometry (1:100-1:260) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal(12-D1) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | CD_antigen=CD6 antibody |
| CD6 antibody | |
| CD6 antigen Tp120 antibody | |
| CD6 molecule antibody | |
| CD6_HUMAN antibody | |
| FLJ44171 antibody | |
| OX52 antibody | |
| T cell differentiation antigen CD6 antibody | |
| T-cell differentiation antigen CD6 antibody | |
| T12 antibody | |
| TP120 antibody |
Target information
Cell adhesion molecule that mediates cell-cell contacts and regulates T-cell responses via its interaction with ALCAM/CD166. Contributes to signaling cascades triggered by activation of the TCR/CD3 complex. Functions as costimulatory molecule; promotes T-cell activation and proliferation. Contributes to the formation and maturation of the immunological synapse. Functions as calcium-dependent pattern receptor that binds and aggregates both Gram-positive and Gram-negative bacteria. Binds both lipopolysaccharide (LPS) from Gram-negative bacteria and lipoteichoic acid from Gram-positive bacteria. LPS binding leads to the activation of signaling cascades and down-stream MAP kinases. Mediates activation of the inflammatory response and the secretion of pro-inflammatory cytokines in response to LPS.
Provider
Erpantech Laboratory