Anti-CD46 antibody
Specifications
| Product Cat#: | AB-06-0932 |
| Product type: | Primary antibody |
| Antigen: | CD46 |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot ( 1:880-1:2200 ); Immunohistochemistry ( 1:90-1:220 ); Immunocytochemistry ( 1:100-1:300 ); |
| Reactivity: | Rat and Human |
| Clonality (clone number): | Monoclonal ( JB25-49 ) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer ( pH7.4 ), 1 % BSA, 40 % glycerol, 0.05 % NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | AHUS2 Antibody |
| Antigen Defined by Monoclonal Antibody TRA 2 10 Antibody | |
| Antigen Identified by Monoclonal Antibody TRA 2 10 Antibody | |
| CD46 Antibody | |
| CD46 Antigen Antibody | |
| CD46 Antigen Complement Regulatory Protein Antibody | |
| CD46 Molecule Antibody | |
| CD46 Molecule Complement Regulatory Protein Antibody | |
| Complement Membrane Cofactor Protein Antibody | |
| MCP Antibody | |
| MCP_HUMAN Antibody | |
| Measles Virus Receptor Antibody | |
| Membrane Cofactor Protein (CD46, Trophoblast-lymphocyte Cross-reactive Antigen) Antibody | |
| Membrane Cofactor Protein Antibody | |
| MGC26544 Antibody | |
| MIC10 Antibody | |
| TLX Antibody | |
| TRA2.10 Antibody | |
| Trophoblast Leucocyte Common AntigenAntibody | |
| Trophoblast Leucocyte common Antigen Antibody |
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Target information
Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity.
Provider
Erpantech Laboratory
