Anti-CD40L antibody
Specifications
| Product Cat#: | AB-06-0925 |
| Product type: | Primary antibody |
| Antigen: | CD40L |
| Immunogen: | recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot ( 1:600-1:1800 ); Immunohistochemistry ( 1:90-1:260 ); Immunocytochemistry ( 1:110-1:300 ); Flow Cytometry ( 1:80-1:200 ) |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Monoclonal（JM11-34） |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer ( pH7.4 ), 1 % BSA, 40 % glycerol, 0.05 % NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | CD 40L Antibody |
| CD154 Antibody | |
| CD40 Antigen Ligand Antibody | |
| CD40 Ligand Antibody | |
| CD40 Ligand, Soluble Form Antibody | |
| CD40-L Antibody | |
| CD40L Antibody | |
| CD40L_HUMAN Antibody | |
| CD40LG Antibody | |
| gp39 Antibody | |
| hCD40L Antibody | |
| HIGM1 Antibody | |
| IGM Antibody | |
| IMD3 Antibody | |
| T B cell Activating Molecule Antibody | |
| T BAM Antibody | |
| T-cell Antigen Gp39 Antibody | |
| TNF-related Activation Protein Antibody | |
| TNFSF5 Antibody | |
| TrAP Antibody | |
| Tumor Necrosis Factor (ligand) Superfamily Sember 5 Antibody | |
| Tumor Necrosis Factor Ligand Superfamily Sember 5 Antibody |
Target information
Cytokine that binds to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation. Induces the activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells. Induces tyrosine phosphorylation of isoform 3 of CD28. Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL4. Involved in immunoglobulin class switching (By similarity).Release of soluble CD40L from platelets is partially regulated by GP IIb/IIIa, actin polymerization, and a matrix metalloproteinases (MMP) inhibitor-sensitive pathway.
Provider
Erpantech Laboratory
