Anti-CD22 antibody
Specifications
| Product Cat#: | AB-06-0882 |
| Product type: | Primary antibody |
| Antigen: | CD22 |
| Immunogen: | Recombinant protein |
| Species immunized: | Mouse |
| Isotype: | IgG |
| Applications: | Western Blot ( 1:300-1:1000 ); Immunohistochemistry ( 1:80-1:200 ); Immunocytochemistry ( 1:80-1:200 ); Flow Cytometry ( 1:80-1:200 ) |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Monoclonal ( C4-H1 ) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer ( pH7.4 ), 1 % BSA, 40 % glycerol, 0.05 % NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | B Cell Receptor CD22 Precursor Antibody |
| B lymphocyte Cell Adhesion Molecule Antibody | |
| B-cell Receptor CD22 Antibody | |
| B-lymphocyte Cell Adhesion Molecule Antibody | |
| BL CAM Antibody | |
| BL-CAM Antibody | |
| BLCAM Antibody | |
| CD 22 Antibody | |
| CD22 Antibody | |
| CD22 Antigen Antibody | |
| CD22 MoleculeAntibody | |
| CD22 Protein Antibody | |
| CD22_HUMAN Antibody | |
| Lectin 2 Antibody | |
| Leu14 Antibody | |
| Lyb8 Antibody | |
| MGC130020 Antibody | |
| Sialic Acid Binding Ig like Lectin 2 Antibody | |
| Sialic Acid Binding Immunoglobulin Like Lectin 2 Antibody | |
| Sialic Acid-binding Ig-like Lectin 2Antibody | |
| SIGLEC 2 Antibody | |
| Siglec-2 Antibody | |
| SIGLEC2 Antibody | |
| T Cell Surface Antigen Leu 14 Antibody | |
| T-cell Surface Antigen Leu-14 Antibody |
Target information
Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
Provider
Erpantech Laboratory
