Anti-CD14 antibody
Specifications
| Product Cat#: | AB-06-0850 |
| Product type: | Primary antibody |
| Antigen: | CD14 |
| Immunogen: | Synthetic peptide (KLH-coupled) within human CD14 150-210 aa. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot ( 1:800-1:2000 ); Immunocytochemistry ( 1:80-1:200 ); Flow Cytometry ( 1:80-1:200 ) |
| Reactivity: | Mouse and Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer ( pH7.4 ), 1 % BSA, 40 % glycerol, 0.05 % NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Peptide affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | CD 14 Antibody |
| CD_antigen=CD14 Antibody | |
| CD14 Antibody | |
| CD14 Antigen Antibody | |
| CD14 Molecule Antibody | |
| CD14_HUMAN Antibody | |
| LPS-R Antibody | |
| Mo2 Antibody | |
| Monocyte Differentiation Antigen CD14 Antibody | |
| Monocyte Differentiation Antigen CD14 Urinary Form Antibody | |
| Monocyte Differentiation Antigen CD14, Membrane-bound Form Antibody | |
| Myeloid Cell Specific Leucine Rich Glycoprotein Antibody | |
| Myeloid Cell-specific Leucine-rich Glycoprotein Antibody |
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Target information
Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. Binds electronegative LDL (LDL–) and mediates the cytokine release induced by LDL–.
Provider
Erpantech Laboratory
