Anti-CD11b antibody
Specifications
| Product Cat#: | AB-06-0836 |
| Product type: | Primary antibody |
| Antigen: | CD11b |
| Immunogen: | Recombinant protein |
| Species immunized: | Mouse |
| Isotype: | IgG2b |
| Applications: | Immunohistochemistry ( 1:80-1:200 ); Immunocytochemistry ( 1:80-1:200 ); Immunocytochemistry ( 1:80-1:200 ) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal ( 4-6 ) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer ( pH7.4 ), 1 % BSA, 40 % glycerol, 0.05 % NaN3. |
| Concentration: | 2 mg/ml |
| Purity: | Protein G affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Antigen CD11b ( p170 ) Antibody |
| Antigen CD11b p170 Antibody | |
| CD11 Antigen Like Family Member B Antibody | |
| CD11 Antigen-like Family Member B Antibody | |
| CD11b Antibody | |
| CD11b/CD18 Antibody | |
| CD49d Antibody | |
| Cell Surface Glycoprotein MAC-1 Subunit Alpha Antibody | |
| Complement Component 3 Receptor 3 Subunit Antibody | |
| Complement Component Receptor 3 Alpha Antibody | |
| Complement Receptor type 3, Alpha Subunit Antibody | |
| CR 3 Alpha Chain (CR3A) Antibody | |
| CR 3 Alpha Chain Antibody | |
| CR-3 Alpha Chain Antibody | |
| CR3 Antibody | |
| CR3AAntibody | |
| F730045J24Rik Antibody | |
| Integrin Alpha M Antibody | |
| Integrin Aalpha M chain Antibody | |
| Integrin Alpha-M Antibody | |
| Integrin Beta 2 Alpha Subunit Antibody | |
| Integrin Subunit Alpha M antibody | |
| Integrin, Alpha M (Complement Component 3 Receptor 3 Subunit) Antibody | |
| ITAM_HUMAN Antibody | |
| ITGAM Antibody | |
| Leukocyte Adhesion Receptor MO1 Antibody | |
| Ly-40 Antibody | |
| MAC 1 Antibody | |
| Mac-1a Antibody | |
| MAC1 Antibody | |
| Mac1, Alpha Subunit Antibody | |
| MAC1A Antibody | |
| Macrophage Antigen Alpha Polypeptide Antibody | |
| MGC117044 Antibody | |
| Mo1, Alpha Subunit Antibody | |
| MO1A Antibody | |
| Neutrophil Adherence Receptor Alpha M subunit Antibody | |
| Neutrophil Adherence Receptor Antibody | |
| SLEB6 Antibody |
Target information
Integrin ITGAM/ITGB2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin ITGAM/ITGB2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. Regulates neutrophil migration. In association with beta subunit ITGB2/CD18, required for CD177-PRTN3-mediated activation of TNF primed neutrophils. May regulate phagocytosis-induced apoptosis in extravasated neutrophils (By similarity). May play a role in mast cell development (By similarity). Required with TYROBP/DAP12 in microglia to control production of microglial superoxide ions which promote the neuronal apoptosis that occurs during brain development (By similarity).
Provider
Erpantech Laboratory
