Anti-CD101 antibody
Specifications
| Product Cat#: | AB-06-0830 |
| Product type: | Primary antibody |
| Antigen: | CD101 |
| Immunogen: | KLH conjugated synthetic peptide derived from human CD101 51-150/1021 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot ( 1:800-1:2000 ); Immunocytochemistry ( 1-3 μg/Test ); Immunofluorescence; Flow Cytometry ( 1:80-1:200 ) |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer ( pH7.4 ), 1 % BSA, 40 % glycerol, 0.03 % Proclin300. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified. |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | IGSF2 |
| Immunoglobulin Superfamily Member 2 | |
| Leukocyte Surface Protein | |
| V7 | |
| V7 LSB | |
| IGSF2_HUMAN | |
| IgSF2 | |
| Cell Surface Glycoprotein V7 | |
| Glu-Trp-Ile EWI Motif-containing Protein 101 | |
| EWI-101 | |
| CD101. |
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Target information
Plays a role as inhibitor of T-cells proliferation induced by CD3. Inhibits expression of IL2RA on activated T-cells and secretion of IL2. Inhibits tyrosine kinases that are required for IL2 production and cellular proliferation. Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and subsequent CD3-induced changes in intracellular free calcium. Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus. Plays a role in the inhibition of T-cell proliferation via IL10 secretion by cutaneous dendritic cells. May be a marker of CD4(+) CD56(+) leukemic tumor cells.
Provider
Erpantech Laboratory