Anti-CaV2.3 antibody
Specifications
| Product Cat#: | AB-06-0781 |
| Product type: | Primary antibody |
| Antigen: | CaV2.3 |
| Immunogen: | Synthetic peptide within rat CaV2.3 aa 860-910 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:550); Immunohistochemistry (1:55-1:200); Immunocytochemistry (1:55-1:200); Flow Cytometry (1:55-1:100) |
| Reactivity: | Mouse, Rat, Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1mg/ml |
| Purity: | Antigen affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | alpha-1 polypeptide antibody |
| BII antibody | |
| Brain calcium channel II antibody | |
| CAC 1E antibody | |
| CAC1E antibody | |
| CAC1E_HUMAN antibody | |
| CACH 6 antibody | |
| CACH6 antibody | |
| CACNA1E antibody | |
| Cacnl1 a6 antibody | |
| CACNL1A6 antibody | |
| Calcium channel antibody | |
| Calcium channel, L type, alpha 1 polypeptide, isoform 6 antibody | |
| calcium channel, R type antibody | |
| Cav 2.3 antibody | |
| Cchra 1 antibody | |
| Cchra1 antibody | |
| isoform 6 antibody | |
| L type antibody | |
| Voltage dependent R type calcium channel subunit alpha 1E antibody | |
| Voltage gated calcium channel subunit alpha Cav2.3 antibody | |
| Voltage-dependent R-type calcium channel subunit alpha-1E antibody | |
| Voltage-gated calcium channel subunit alpha Cav2.3 antibody |
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Target information
Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells (PubMed:30343943). They are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. R-type calcium channels belong to the ‘high-voltage activated’ (HVA) group and are blocked by nickel. They are however insensitive to dihydropyridines (DHP). Calcium channels containing alpha-1E subunit could be involved in the modulation of firing patterns of neurons which is important for information processing.
Provider
Erpantech Laboratory
