Anti-Caldesmon antibody
Specifications
| Product type: | Primary antibody |
| Antigen: | Caldesmon |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-2000); Immunohistochemistry (1:100-1:200); Immunocytochemistry/Immunofluorescence (1:100-1:200); Immunoprecipitation; Flow Cytometry (1:40-1:100) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal, SU03-19 |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 0.05% NaN3 and 40% Glycerol. |
| Concentration: | 1mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | CAD antibody |
| CALD 1 antibody | |
| CALD1 antibody | |
| CALD1_HUMAN antibody | |
| Caldesmon 1 antibody | |
| Caldesmon 1 Isoform 1 antibody | |
| Caldesmon 1 Isoform 2 antibody | |
| Caldesmon 1 Isoform 3 antibody | |
| Caldesmon 1 Isoform 4 antibody | |
| Caldesmon 1 Isoform 5 antibody | |
| Caldesmon antibody | |
| Caldesmon1 antibody | |
| CDM antibody | |
| H CAD antibody | |
| HCAD antibody | |
| L CAD antibody | |
| LCAD antibody | |
| MGC21352 antibody | |
| NAG22 antibody |
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Target information
Actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments). Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin. This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin. Interacts with actin, myosin, two molecules of tropomyosin and with calmodulin. Also play an essential role during cellular mitosis and receptor capping. Involved in Schwann cell migration during peripheral nerve regeneration (By similarity).
Provider
Erpantech Laboratory