Anti-CACNA1C antibody
Specifications
| Product type: | Primary antibody |
| Antigen: | CACNA1C |
| Isotype: | IgG |
| Species immunized: | Rabbit |
| Immunogen: | Synthetic peptide within human CACNA1C aa 800-880 |
| Applications: | Dot Blot (1:400-1:1000); Immunohistochemistry (1:40-1:200); Immunocytochemistry (1:400-1:2000); Flow Cytometry (1:40-1:100) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 0.5% BSA, 0.05% NaN3 and 50% Glycerol. |
| Concentration: | 1mg/ml |
| Purity: | Antigen affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Alpha-1 polypeptide antibody |
| Cardiac muscle antibody | |
| Isoform 1 antibody | |
| L type antibody | |
| CAC1C_HUMAN antibody | |
| CACH 2 antibody | |
| CACH2 antibody | |
| CACN 2 antibody | |
| CACN2 antibody | |
| CACNA1C antibody | |
| CACNL1A1 antibody | |
| Calcium channel antibody | |
| Calcium channel cardic dihydropyridine sensitive alpha 1 subunit antibody | |
| Calcium channel L type alpha 1 polypeptide isoform 1 cardiac muscle antibody | |
| Calcium channel voltage dependent L type alpha 1C subunit antibody | |
| CaV1.2 antibody | |
| CCHL1A1 antibody | |
| DHPR alpha 1 antibody | |
| DHPR alpha 1 subunit antibody | |
| LQT8 antibody | |
| TS antibody | |
| Voltage dependent L type calcium channel alpha 1C subunit antibody | |
| Voltage dependent L type calcium channel subunit alpha 1C antibody | |
| Voltage gated calcium channel alpha subunit Cav1.2 antibody | |
| Voltage gated calcium channel subunit alpha Cav1.2 antibody | |
| Voltage gated L type calcium channel Cav1.2 alpha 1 subunit, splice variant 10* antibody |
Target information
Pore-forming, alpha-1C subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents (PubMed:8392192, PubMed:7737988, PubMed:9087614, PubMed:9013606, PubMed:9607315, PubMed:12176756, PubMed:17071743, PubMed:11741969, PubMed:8099908, PubMed:12181424, PubMed:29078335, PubMed:29742403, PubMed:16299511, PubMed:20953164, PubMed:15454078, PubMed:15863612, PubMed:17224476, PubMed:24728418, PubMed:26253506, PubMed:27218670). Mediates influx of calcium ions into the cytoplasm, and thereby triggers calcium release from the sarcoplasm (By similarity). Plays an important role in excitation-contraction coupling in the heart. Required for normal heart development and normal regulation of heart rhythm (PubMed:15454078, PubMed:15863612, PubMed:17224476, PubMed:24728418, PubMed:26253506). Required for normal contraction of smooth muscle cells in blood vessels and in the intestine. Essential for normal blood pressure regulation via its role in the contraction of arterial smooth muscle cells (PubMed:28119464). Long-lasting (L-type) calcium channels belong to the ‘high-voltage activated’ (HVA) group (Probable).
Provider
Erpantech Laboratory
