Anti-C6orf25 antibody
Specifications
| Product type: | Primary antibody |
| Antigen: | C6orf25 |
| Isotype: | IgG |
| Species immunized: | Rabbit |
| Immunogen: | KLH conjugated synthetic peptide derived from human C6orf25 1-100/241 |
| Applications: | Western Blot (1:400-1:2000) |
| Reactivity: | Human, Mouse, Rat, Cow, Sheep |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 1%BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Chromosome 6 open reading frame 25 |
| G6b | |
| G6B protein | |
| Immunoglobulin receptor | |
| MGC142279 | |
| MGC142281 | |
| NG31 | |
| Protein G6b |
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Target information
Inhibitory receptor that acts as a critical regulator of hematopoietic lineage differentiation, megakaryocyte function and platelet production (PubMed:12665801, PubMed:17311996, PubMed:27743390). Inhibits platelet aggregation and activation by agonists such as ADP and collagen-related peptide (PubMed:12665801). This regulation of megakaryocate function as well as platelet production ann activation is done through the inhibition (via the 2 ITIM motifs) of the receptors CLEC1B and GP6:FcRgamma signaling (PubMed:17311996). Appears to operate in a calcium-independent manner (PubMed:12665801).
Provider
Erpantech Laboratory
