Anti-C4 antibody
Specifications
| Product type: | Primary antibody |
| Antigen: | C4 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Immunogen: | Recombinant protein |
| Applications: | Western Blot (1:100-1:500); Immunocytochemistry/Immunofluorescence (1:100-1:200); Immunohistochemistry (1:100-1:200) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal, JM88-13 |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 1%BSA, 0.05%NaN3 and 40% Glycerol. |
| Concentration: | 1mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Acidic C4 antibody |
| Acidic complement C4 antibody | |
| Basic C4 antibody | |
| Basic complement C4 antibody | |
| C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2 antibody | |
| C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3 antibody | |
| C4, Chido form antibody | |
| C4, Rodgers from antibody | |
| C4A anaphylatoxin antibody | |
| C4A antibody | |
| C4A2 antibody | |
| C4A3 antibody | |
| C4A4 antibody | |
| C4A6 antibody | |
| C4AD antibody | |
| C4B antibody | |
| C4B_2 antibody | |
| C4B1 antibody | |
| C4B12 antibody | |
| C4B2 antibody | |
| C4B3 antibody | |
| C4BD antibody | |
| C4F antibody | |
| C4S antibody | |
| CH antibody | |
| Chido form of C4 antibody | |
| CO4 antibody | |
| CO4A_HUMAN antibody | |
| Complement C4 gamma chain antibodycomplement C4-A antibody | |
| Complement C4-B antibody | |
| Complement C4-B-like antibody | |
| Complement C4B1a antibody | |
| Complement component 4A (Rodgers blood group) antibody | |
| Complement component 4A antibody | |
| Complement component 4B (Chido blood group), copy 2 antibody | |
| Complement component 4B (Childo blood group) antibody | |
| Complement component 4B antibody | |
| Complement component 4F antibody | |
| Complement component 4S antibody | |
| CPAMD2 antibody | |
| CPAMD3 antibody |
Target information
Non-enzymatic component of C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes. C4A isotype is responsible for effective binding to form amide bonds with immune aggregates or protein antigens, while C4B isotype catalyzes the transacylation of the thioester carbonyl group to form ester bonds with carbohydrate antigens.Derived from proteolytic degradation of complement C4, C4a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.
Provider
Erpantech Laboratory
