Anti-C20orf72 antibody
Specifications
| Product type: | Primary antibody |
| Antigen: | C20orf72 |
| Isotype: | IgG |
| Species immunized: | Rabbit |
| Immunogen: | KLH conjugated synthetic peptide derived from human c20orf72 201-300/344 |
| Applications: | Western Blot (1:400-1:2000) |
| Reactivity: | Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, Sheep |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 1%BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Chromosome 20 open reading frame 72 |
| Hypothetical protein LOC92667 | |
| MGME1_HUMAN. |
Show More
Target information
Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5′-3′ exonuclease activity but is also capable of endoduclease activity on linear substrates. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA-primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair. Specifically binds 5-hydroxymethylcytosine (5hmC)-containing DNA in stem cells.
Provider
Erpantech Laboratory
