Anti-Bub3 antibody
Specifications
| Product type: | Primary antibody |
| Antigen: | Bub3 |
| Immunogen: | Recombinant protein corresponding to the N-terminus of human Bub3. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:2000); Immunohistochemistry (1:100-1:200); Immunocytochemistry/Immunofluorescence (1:100-1:200); Immunoprecipitation; Flow Cytometry (1:40-1:100) |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Monoclonal, JG38-81 |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1mg/ml |
| Purity: | Protein A/G affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Aa2-050 antibody |
| AU019800 antibody | |
| AU021329 antibody | |
| AU043350 antibody | |
| AW146323 antibody | |
| BUB 3 antibody | |
| BUB 3L antibody | |
| BUB3 (budding uninhibited by benzimidazoles 3, yeast) homolog antibody | |
| Bub3 antibody | |
| BUB3 budding uninhibited by benzimidazoles 3 homolog antibody | |
| BUB3 mitotic checkpoint protein antibody | |
| BUB3_HUMAN antibody | |
| BUB3L antibody | |
| Budding uninhibited by benomyl antibody | |
| Budding uninhibited by benzimidazoles 3 antibody | |
| Budding uninhibited by benzimidazoles 3 homolog (S. cerevisiae) antibody | |
| Budding uninhibited by benzimidazoles 3 homolog (yeast) antibody | |
| Budding uninhibited by benzimidazoles 3 homolog antibody | |
| Budding uninhibited by benzimidazoles 3, S. cerevisiae, homolog of antibody | |
| C78067 antibody | |
| hBUB3 antibody | |
| Mitotic checkpoint component antibody | |
| Mitotic checkpoint protein bub3 antibody | |
| OTTHUMP00000020679 antibody | |
| OTTHUMP00000020680 antibody |
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Target information
Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubule (K-MT) attachments. Promotes the formation of stable end-on bipolar attachments. Necessary for kinetochore localization of BUB1. Regulates chromosome segregation during oocyte meiosis. The BUB1/BUB3 complex plays a role in the inhibition of anaphase-promoting complex or cyclosome (APC/C) when spindle-assembly checkpoint is activated and inhibits the ubiquitin ligase activity of APC/C by phosphorylating its activator CDC20. This complex can also phosphorylate MAD1L1.
Provider
Erpantech Laboratory
