Anti-Beta-Glucan Receptor antibody
Specifications
| Product Cat#: | AB-06-0500 |
| Product type: | Primary antibody |
| Antigen: | Beta-Glucan Receptor |
| Immunogen: | KLH conjugated synthetic peptide derived from human Dectin-1 41-140/247 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:2000) |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A/G affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Dectin1 |
| Dectin-1 | |
| Dectin 1 | |
| CLECSF12 | |
| C-type lectin domain family 7 member A | |
| beta Glucan Receptor | |
| Beta GR | |
| BGR | |
| C type calcium dependent carbohydrate recognition domain lectin superfamily member 12 | |
| Clec7a | |
| CANDF4 | |
| DECTIN1 | |
| CLEC7A protein | |
| Clecsf12 | |
| Dectin 1 | |
| DECTIN 1 receptor | |
| Dectin1 | |
| Dendritic cell associated C type lectin 1 | |
| Lectin like receptor 1 | |
| beta Glucan Receptor |
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Target information
Lectin that functions as pattern receptor specific for beta-1,3-linked and beta-1,6-linked glucans, such as cell wall constituents from pathogenic bacteria and fungi. Necessary for the TLR2-mediated inflammatory response and for TLR2-mediated activation of NF-kappa-B. Enhances cytokine production in macrophages and dendritic cells. Mediates production of reactive oxygen species in the cell. Mediates phagocytosis of C.albicans conidia. Binds T-cells in a way that does not involve their surface glycans and plays a role in T-cell activation. Stimulates T-cell proliferation.
Provider
Erpantech Laboratory
