Anti-Bcl-2 antibody
Specifications
| Product Cat#: | AB-06-0475 |
| Product type: | Primary antibody |
| Antigen: | Bcl-2 |
| Immunogen: | Recombinant protein within human BCL-2 aa 1-200. |
| Species immunized: | Mouse |
| Isotype: | IgG2b |
| Applications: | Western Blot (1:200-1:500); Immunocytochemistry (1:100-1:200); Flow Cytometry (1:40-1:100) |
| Reactivity: | Human, Mouse |
| Clonality (clone number): | Monoclonal, F7-1-A1 |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 2 mg/ml |
| Purity: | Protein A/G affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Apoptosis regulator Bcl 2 antibody |
| Apoptosis regulator Bcl-2 antibody | |
| Apoptosis regulator Bcl2 antibody | |
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Target information
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (PubMed:17418785).
Provider
Erpantech Laboratory
