Anti-Bcl-2 antibody
Specifications
| Product Cat#: | AB-06-0472 |
| Product type: | Primary antibody |
| Antigen: | Bcl-2 |
| Immunogen: | Synthetic peptide within human BCL2 35-60 aa |
| Species immunized: | Mouse |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:1000); Immunohistochemistry (1:400-1:1000) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal, 9F1 |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 0.5% BSA, 50% glycerol, 0.05% NaN3. |
| Concentration: | 2 mg/ml |
| Purity: | Antigen affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Apoptosis regulator Bcl 2 antibody |
| Apoptosis regulator Bcl-2 antibody | |
| Apoptosis regulator Bcl2 antibody | |
| AW986256 antibody | |
| B cell CLL/lymphoma 2 antibody | |
| B cell leukemia/lymphoma 2 antibody | |
| Bcl-2 antibody | |
| Bcl2 antibody | |
| BCL2_HUMAN antibody | |
| C430015F12Rik antibody | |
| D630044D05Rik antibody | |
| D830018M01Rik antibody | |
| Leukemia/lymphoma, B-cell, 2 antibody | |
| Oncogene B-cell leukemia 2 antibody | |
| PPP1R50 antibody | |
| Protein phosphatase 1, regulatory subunit 50 antibody |
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Target information
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (PubMed:17418785).
Provider
Erpantech Laboratory
