Anti-ATG16L1 antibody
Specifications
| Product Cat#: | AB-06-0402 |
| Product type: | Primary antibody |
| Antigen: | ATG16L1 |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:2000) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal, JU30-62 |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Peptide affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | A16L1_HUMAN antibody |
| APG16 like 1 antibody | |
| APG16-like 1 antibody | |
| APG16L antibody | |
| APG16L beta antibody | |
| ATG16 autophagy related 16 like 1 antibody | |
| ATG16 autophagy related 16-like 1 (S. cerevisiae) antibody | |
| ATG16A antibody | |
| ATG16L antibody | |
| Atg16l1 antibody | |
| Autophagy related protein 16 1 antibody | |
| Autophagy-related protein 16-1 antibody | |
| FLJ00045 antibody | |
| FLJ10035 antibody | |
| FLJ10828 antibody | |
| FLJ22677 antibody | |
| IBD10 antibody | |
| OTTHUMP00000164391 antibody | |
| OTTHUMP00000164393 antibody | |
| OTTHUMP00000165876 antibody | |
| OTTHUMP00000165877 antibody | |
| WD repeat domain 30 antibody | |
| WDR30 antibody |
Target information
Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane (PubMed:24553140, PubMed:23376921, PubMed:24954904, PubMed:27273576, PubMed:23392225). Regulates mitochondrial antiviral signaling (MAVS)-dependent type I interferon (IFN-I) production (PubMed:25645662). Negatively regulates NOD1- and NOD2-driven inflammatory cytokine response (PubMed:24238340). Instead, promotes with NOD2 an autophagy-dependent antibacterial pathway (PubMed:20637199). Plays a role in regulating morphology and function of Paneth cell (PubMed:18849966).
Provider
Erpantech Laboratory
