Anti-ATF7 antibody
Specifications
| Product Cat#: | AB-06-0395 |
| Product type: | Primary antibody |
| Antigen: | ATF7 |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:1000); Immunohistochemistry (1:40-1:200); Flow Cytometry (1:40-1:100); Immunocytochemistry/Immunofluorescence (1:40-1:200) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal, JJ2-072 |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A/G affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | 1110012F10Rik antibody |
| 9430065F09Rik antibody | |
| Activating transcription factor 7 antibody | |
| AI549878 antibody | |
| ATF7 antibody | |
| Atf7 protein antibody | |
| ATF7_HUMAN antibody | |
| ATFA antibody | |
| C130020M04Rik antibody | |
| cAMP-dependent transcription factor ATF-7 antibody | |
| Cyclic AMP-dependent transcription factor ATF 7 antibody | |
| Cyclic AMP-dependent transcription factor ATF-7 antibody | |
| MGC31554 antibody | |
| MGC57182 antibody | |
| Transcription factor ATF A antibody | |
| Transcription factor ATF-A antibody |
Target information
Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5′-GTGACGT[AG][AG]-3′), a sequence present in many viral and cellular promoters. Activator of the NF-ELAM1/delta-A site of the E-selectin promoter. Has no intrinsic transcriptional activity, but activates transcription on formation of JUN or FOS heterodimers. Also can bind TRE promoter sequences when heterodimerized with members of the JUN family.
Isoform 4 acts as a dominant repressor of the E-selectin/NF-ELAM1/delta-A promoter.
Isoform 5 acts as a negative regulator, inhibiting both ATF2 and ATF7 transcriptional activities. It may exert these effects by sequestrating in the cytoplasm the Thr-53 phosphorylating kinase, preventing activation.
Provider
Erpantech Laboratory
